13228
clinical study

Performance and Reliability of an Artificial Intelligence Algorithm for the Automated Detection of Incidental Abdominal Aortic Aneurysm

Materials & Methods

A retrospective study analyzed emergency CT scans of the abdomen and pelvis from Yale New Haven Hospital (July 31 to Dec. 31, 2020 and Jan. 1 to May 10, 2021). An FDA-cleared AI algorithm (Aidoc) processed the images, while a natural language processing (NLP) program evaluated the corresponding radiology reports. Cases where the AI detected an abdominal aortic aneurysm (AAA), but NLP did not, were flagged as potential discrepancies and independently reviewed by an emergency radiologist. 

Results

A total of 4,023 abdominal and pelvic CT exams were analyzed, with 98.3% (3,955) reported as negative for abdominal aortic aneurysm (AAA) by natural language processing (NLP). AI flagged 16 potential discrepancies, and secondary review confirmed previously undocumented AAA in 31% (5/16) of these cases, increasing detection by 7.4% (5/68) compared to radiologists alone. In 69% (11/16) of false-positive cases, AI overestimated aortic diameter due to lumen obliquity, which was corrected using multiplanar reconstruction.

Conclusions

AI algorithms can potentially enhance incidental AAA detection on CT imaging but require further advancements before being viable for fully automated clinical screening.

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Deepak Srikant

<p>Deepak Srikant is a global marketing executive with over 20 years of experience, specializing in the commercialization of medical devices and digital health solutions. He has a proven track record in driving growth, having led successful go-to-market strategies, product launches and market expansions across the U.S. and EMEA.</p> <p>Srikant’s expertise extends to upstream and downstream marketing, professional education and sales enablement. His leadership at companies such as Silk Road Medical (acquired by Boston Scientific) and Aptus Endosystems (acquired by Medtronic) has consistently resulted in revenue growth, enhanced customer retention and successful product adoption.</p> <p>Srikant holds an MBA from the Yale School of Management and a bachelor’s degree in mechanical engineering from Rensselaer Polytechnic Institute. Currently, he leads product marketing for Aidoc’s cardiovascular service line.</p>

Laci Costa

<p>Laci Costa is the Director of Neurovascular Product Marketing at Aidoc. She leads marketing and commercial strategy for the neuro AI portfolio of products. She has 16 years of experience working in the medical device and healthcare industry, with over 12 years dedicated to neurovascular solutions.</p> <p>Costa’s known for her expertise in the neurovascular industry, go-to-market experience with new technologies and upstream and downstream product marketing leadership. She’s held various leadership positions in product marketing, clinical education and professional affairs spanning across start-up organizations to large publicly traded companies.</p> <p>Costa holds a bachelor’s degree in psychology from the University of Oklahoma and an MBA from USC Marshall School of Business.</p>

Ayden Jacob, MD, MSc

<p>Ayden Jacob, MD, MSc, is a physician-engineer with expertise in AI, data science and healthcare economics. He’s passionate about leveraging AI and data science to solve complex healthcare issues through the specific prism of economics and finance. At Aidoc, Dr. Jacob’s work focuses on quantifying the clinical and financial impact of innovative AI solutions deployed throughout the healthcare ecosystem.</p> <p>Dr. Jacob’s diverse expertise reflects a commitment to advancing healthcare through data-driven solutions that enhance both patient outcomes and operational effectiveness. A graduate of Yeshiva University and the University of Oxford, Dr. Jacob employs an interdisciplinary approach to innovating at the intersection of clinical medicine, engineering and informatics.</p>