Explore a comprehensive framework for integrating AI into clinical practice ensuring trust, compliance and real-world impact.
3.6 billion. That’s the number of diagnostic radiology exams, including x-rays, that are taken annually throughout the world, according to the World Health Organization (WHO). With the frequent use of x-rays and their role in diagnosis of sometimes time-sensitive conditions, like fractures and infections, AI can have a significant impact on speed, accuracy and efficiency. But how do they work together?
For x-rays, AI algorithms use computer vision — a field that enables machines to see and interpret data — and deep learning — a type of machine learning that analyzes data at exceptional speeds without compromising accuracy — to detect patterns, classify conditions and assist in diagnosis.
Step 1: X-Ray AI Pre-Process
In the first step, the x-ray is uploaded. It can be uploaded via camera, direct capture or from PACS. The x-ray AI then normalizes the pixel values based on the acquisition metadata to ensure consistent interpretation across studies. This normalization adjusts the intensity range, so the brightness and contrast reflect meaningful anatomical detail.
Step 2: X-Ray AI Feature Extraction
Once uploaded and pre-processed, the image is then processed layer by layer using a convolutional neural network (CNN) — a neural network designed to detect patterns in images (think: edges, shapes, textures). The first layers detect simple patterns, like edges and textures, while the later layers delve into more complex anatomical cues that help the model spot subtle pathologies. These are then used to create a feature map showing visual patterns that might indicate disease.
Step 3: X-Ray AI Classification/Detection
With information gathered, the x-ray AI (based on trained data) classifies the image — for example as normal or fracture — or detects specific findings — for example nodules — with bounding boxes. In some cases, a model may generate a probability score to show the confidence in the diagnosis.
Step 4: X-Ray AI Annotation/Visualization
Next, AI may overlay the findings on the x-ray. This can be with bounding boxes, explainability tools or heatmaps, providing transparency into why the AI made the decision. The radiologist can then use these visual tools to verify or challenge the results from the AI.
Step 5: Integrating X-Ray AI Findings into the Workflow
Depending on the health system’s setup, the results may be sent to the radiologist’s worklist or embedded in the PACS viewer. These findings can then be prioritized if the case appears to be critical, pre-filled into report sections or trigger alerts for follow-up care.
Here’s an example of how Aidoc’s AI solution has impacted x-ray interpretation.
Enhanced detections. Gleamers’ BoneView solution, deployed at Boston University, completed 480 exams across 24 readers. It resulted in a 16% increase in sensitivity (64.8% to 75.2%) 22% increase in sensitivity rates for multi-fractures exams and 30% decrease in missed fractures.1
As healthcare evolves, we’ll see even more benefits of AI in medical imaging. Today, the impact is very clear. Here are the five key benefits.
Explore these benefits further in our blog — “5 Benefits of AI in Medical Imaging”.
While AI in medical imaging was roughly valued around $1.8 billion in 2025, it’s poised to surpass $14.8 billion by 2032, according to a report from Market.us Media. As more health systems bring AI into the mix, it can impact the field in a variety of ways, including:
For a deeper dive into the future of AI in medical imaging, check out our webinar — “How It Started Versus How It’s Going: AI Early Adopters Discuss How the Technology Has Changed Practice”.
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